Natural and herbal products have been used for centuries throughout the world, in all cultures. The scientific community has begun to show increasing interest in these products, as the benefits become more widely known. Noni began to attract the interest of researchers around the world in this century, and one by one, studies have revealed the wonderful qualities of Noni fruit.
Dr. Ralph Heinicke and Ala Palu are working in the extraction and the structure of the Proxeronine and Xeronine. Dr. Anne Hirazuni Kim is continuing work in Noni and the effects on lung cancer cells called Lewis.The Dr. Mian Yin Wong is working on the first human clinical trial using Noni juice from the University of Illinois Rocaford. Studies are underway in the chemopreventive effects of Noni juice in smokers.
Dr. Fugisawa at the University of Hawaii has investigated the effects of Noni juice and chemotherapy drugs to cancer cells in the sarcoma line 180.
Brigham Young University is investigating specifically the COX-II restriction enzymes. As a result of this investigation, these individuals have discovered Noni's ability to restrict COX-II enzymes without disrupting the operation of the enzymes COX-I.
Scientists are also investigating the properties of Noni juice against bacteria, fungi and parasites. Dr. Ho at Rutgers University is doing studies discovered novel components in Noni. Investigations are in the powerful antioxidant properties of Noni. Research scientists are studying the toxicological properties of Noni allerginicitas and genotoxic.
1. Dr. Ralph Heinicke Keronina and cell regenerationAs a researcher in Hawaii, Dr. Ralph Heinicke discovered the wonderful benefits of the Noni fruit and set out to find the active pharmaceutical ingredient of Noni. Dr. Heinicke had studied for 45 years the effects of alkaloid he discovered and named xeronine. Xeronine is a relatively small alkaloid which is physiologically very active and important for the proper function of all body cells.
In this study, Dr. Heinicke found Noni juice contains appreciable amounts of the precursor of xeronine, which he named "pro-xeronine." The pro-xeronine releases pure xeronine in the intestines by contact with a particular enzyme also found in Noni juice. Dr. Heinicke's theory is that when xeronine is released, it acts at the molecular level to repair damaged cells. Dr. Heinicke states that the primary function of xeronine is to regulate the rigidity and shape of specific proteins. Because these proteins have different functions in cells, this explains how the administration of Noni Juice causes an unbelievably wide range of physiological responses."Some of the problems that drinking Noni juice can help favorably are: high blood pressure, menstrual cramps, arthritis, gastric ulcers, sprains, mental depression, poor digestion, injury, atherosclerosis, problems with blood valves, senility, drug addiction , relief of pain and many more. Although this list seems to be a page torn out of a manual of a man traveling medicine, is probably conservative. " Dr. Heinicke
Anticancer 2.Actividad Noni (Morinda citrifolia) in the Lewis Lung carcinoma implanted intraperitoneally in syngeneic mice. A. Hirazumi, E. Furusawa, S.C. Chou & Y. Hokama, Proc. West. Pharmacol. Soc 37: 145-146 (1994).This is a very significant study by a team of researchers from the University of Hawaii led by Annie Hirazumi. Ms. Hirazumi became interested in studying the Noni fruit for their previous experiences with amazing qualities. His father helped a good friend with Noni juice and later, Annie administered the pure Noni juice a puppy who was dying. The perrrito miraculously recovered and Annie decided to find out more about this incredible fruit.The study by Ms. Hirazumi and colleagues was conducted in laboratory mice (C57BL6 mice specifically), identified as responsive to the cells either injected Lewis Lung Carcinoma. Mice were injected with active cells of Lewis Lung carcinoma (LLC). Without treatment, the mice died between 9 and 12 days after injection of tumor growth. A portion of the injected mice were treated with Noni juice in five separate daily treatments. Noni juice showed a significant increase in lifespan of mice in the experiment (105% -123%), with a total of 9 of the 22 mice surviving for more than 50 days. The experiment was repeated in a different batch of mice, with similar results. The research team concluded that the Noni juice, "seems to act indirectly by increasing the immune istmeña s involving macrophages and / or lymphocytes."
3. Induction of normal phenotypes in RAS transformed cells Damnacanthal Morinda Citrifolia.T. Hiramaysu, M. Imoto, T. Koyano, K. Umezawa letters on Cancer 73 (1993) 161-166In this study, a Japanese team studied the effects of over 500 tropical plant extracts in the cell K-RAS-NR (a precursor of certain types of cancer). Damnacanthal compound, found in the Morinda citrifolia (Noni) proved to be an inhibitor of Ras function. The study: RAS cells were planted in 96 dishes and incubated at 33 ° C for 24 hours.
He added the Noni plant extract and examined the morphology of the cell every day for 5 days. The Ras function was inhibited by the injected plant extract. It is found that this compound has inhibited the activation of early-antigen of Epstein-Barr virus. The extract of Morinda citrifolia was the most effective inhibitor of Ras function among the 500 extracts tested.
Dr. Ralph Heinicke and Ala Palu are working in the extraction and the structure of the Proxeronine and Xeronine. Dr. Anne Hirazuni Kim is continuing work in Noni and the effects on lung cancer cells called Lewis.The Dr. Mian Yin Wong is working on the first human clinical trial using Noni juice from the University of Illinois Rocaford. Studies are underway in the chemopreventive effects of Noni juice in smokers.
Dr. Fugisawa at the University of Hawaii has investigated the effects of Noni juice and chemotherapy drugs to cancer cells in the sarcoma line 180.
Brigham Young University is investigating specifically the COX-II restriction enzymes. As a result of this investigation, these individuals have discovered Noni's ability to restrict COX-II enzymes without disrupting the operation of the enzymes COX-I.
Scientists are also investigating the properties of Noni juice against bacteria, fungi and parasites. Dr. Ho at Rutgers University is doing studies discovered novel components in Noni. Investigations are in the powerful antioxidant properties of Noni. Research scientists are studying the toxicological properties of Noni allerginicitas and genotoxic.
1. Dr. Ralph Heinicke Keronina and cell regenerationAs a researcher in Hawaii, Dr. Ralph Heinicke discovered the wonderful benefits of the Noni fruit and set out to find the active pharmaceutical ingredient of Noni. Dr. Heinicke had studied for 45 years the effects of alkaloid he discovered and named xeronine. Xeronine is a relatively small alkaloid which is physiologically very active and important for the proper function of all body cells.
In this study, Dr. Heinicke found Noni juice contains appreciable amounts of the precursor of xeronine, which he named "pro-xeronine." The pro-xeronine releases pure xeronine in the intestines by contact with a particular enzyme also found in Noni juice. Dr. Heinicke's theory is that when xeronine is released, it acts at the molecular level to repair damaged cells. Dr. Heinicke states that the primary function of xeronine is to regulate the rigidity and shape of specific proteins. Because these proteins have different functions in cells, this explains how the administration of Noni Juice causes an unbelievably wide range of physiological responses."Some of the problems that drinking Noni juice can help favorably are: high blood pressure, menstrual cramps, arthritis, gastric ulcers, sprains, mental depression, poor digestion, injury, atherosclerosis, problems with blood valves, senility, drug addiction , relief of pain and many more. Although this list seems to be a page torn out of a manual of a man traveling medicine, is probably conservative. " Dr. Heinicke
Anticancer 2.Actividad Noni (Morinda citrifolia) in the Lewis Lung carcinoma implanted intraperitoneally in syngeneic mice. A. Hirazumi, E. Furusawa, S.C. Chou & Y. Hokama, Proc. West. Pharmacol. Soc 37: 145-146 (1994).This is a very significant study by a team of researchers from the University of Hawaii led by Annie Hirazumi. Ms. Hirazumi became interested in studying the Noni fruit for their previous experiences with amazing qualities. His father helped a good friend with Noni juice and later, Annie administered the pure Noni juice a puppy who was dying. The perrrito miraculously recovered and Annie decided to find out more about this incredible fruit.The study by Ms. Hirazumi and colleagues was conducted in laboratory mice (C57BL6 mice specifically), identified as responsive to the cells either injected Lewis Lung Carcinoma. Mice were injected with active cells of Lewis Lung carcinoma (LLC). Without treatment, the mice died between 9 and 12 days after injection of tumor growth. A portion of the injected mice were treated with Noni juice in five separate daily treatments. Noni juice showed a significant increase in lifespan of mice in the experiment (105% -123%), with a total of 9 of the 22 mice surviving for more than 50 days. The experiment was repeated in a different batch of mice, with similar results. The research team concluded that the Noni juice, "seems to act indirectly by increasing the immune istmeña s involving macrophages and / or lymphocytes."
3. Induction of normal phenotypes in RAS transformed cells Damnacanthal Morinda Citrifolia.T. Hiramaysu, M. Imoto, T. Koyano, K. Umezawa letters on Cancer 73 (1993) 161-166In this study, a Japanese team studied the effects of over 500 tropical plant extracts in the cell K-RAS-NR (a precursor of certain types of cancer). Damnacanthal compound, found in the Morinda citrifolia (Noni) proved to be an inhibitor of Ras function. The study: RAS cells were planted in 96 dishes and incubated at 33 ° C for 24 hours.
He added the Noni plant extract and examined the morphology of the cell every day for 5 days. The Ras function was inhibited by the injected plant extract. It is found that this compound has inhibited the activation of early-antigen of Epstein-Barr virus. The extract of Morinda citrifolia was the most effective inhibitor of Ras function among the 500 extracts tested.
No hay comentarios:
Publicar un comentario